Hypertrophic Scar Formation and Wound Healing Modulation Fatty Acids as Modulators of Severe Scars

Scar tissue usually generates severe discomfort in the short and long term. Common symptoms include anesthetics sequelae, pruritus, joint malfunction, new wounds on scar surface, pain. There are several treatments for scars, like compression, topical or intralesional steroid infiltration, 5-fluorouracil, dermabrasion, surgeries with tissue. For adult patients, it is easier to choose treatment. However, compression commonly applied children prevent that have adverse effects. This study reports outcomes of 15 patients submitted abdominoplasty, traumatic post-burn treatments, which showed significant changes after continuous use an ointment composed petrolatum, cod liver oil, BHT, Chamomilla recutita (chamomile) Helianthus annuus (sunflower) Prunus amygdalus dulcis (sweet almond) oil. As components stratum corneum, unsaturated fatty acids influence cutaneous structural immune status permeability. They also interfere maturation differentiation corneum inhibit production proinflammatory eicosanoids, reactive species (ROS RNS), cytokines, thereby influencing inflammatory response possibly wound healing. article aims share our experience regular pediatric three months. The increase cytokine at sites, resulting a noninvasive, therapeutical, effective healing scarring modulation, may provide physiopathological explanation fast improvement scars.